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Categories: Peptides & Proteins / Proteins

Product name			KLK7, Recombinant, Human, aa1-181, His-Tag (Kallikrein-7 Isoform 2)
Catalog No			USB-369087
Supplier’s Catalog No			369087
Supplier			US Biologicals
Source antigen			Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight			20.9

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			KLK7, as known as kallikrein-7 isoform 2, is a secreted protein which belongs to the peptidase S1 family and kallikrein subfamily. Members of the kallikrein family are involved in various malignancies such as prostate (PSA, KLK2, KLK15), ovarian (KLK4, KLK5, KLK6, KLK8, KLK10), and breast cancer (KLK10, KLK13, LKL14). This protein is expressed in the skin, a major physiological function of KLK7 is to regulate the desquamation process through proteolysis of the intercellular adhesive structure between corneocytes. Source: Recombinant protein corresponding to aa1-181 from human KLK7, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~20.9kD (190aa) 28-40kD (SDS-PAGE under reducing conditions) AA Sequence: ADPMNEYTVH LGSDTLGDRR AQRIKASKSF RHPGYSTQTH VNDLMLVKLN SQARLSSMVK KVRLPSRCEP PGTTCTVSGW GTTTSPDVTF PSDLMCVDVK LISPQDCTKV YKDLLENSML CAGIPDSKKN ACNGDSGGPL VCRGTLQGLV SWGTFPCGQP NDPGVYTQVC KFTKWINDTM KKHRHHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.