Cytokeratin 19 Fragment (Cyfra 21-1 Antigen)

Catalog No : USB-C9097
578.18€
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Product name Cytokeratin 19 Fragment (Cyfra 21-1 Antigen)
Catalog No USB-C9097
Supplier’s Catalog No C9097
Supplier US Biologicals
Source antigen MCF-7 cell supernatant.
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Purified
Purity Purified by Ion Exchange Chromatography. 0.2um filtered. Known Contaminants: RIA: (Centocor CA-125, Truquant 27.29, Centocor CA 19-9): As reported.
Form Supplied as a liquid in PBS, pH 7.4. No preservatives added.
Reactivity life 12 months
Note For reserch purpose only
Purity Purified by Ion Exchange Chromatography. 0.2um filtered. Known Contaminants: RIA: (Centocor CA-125, Truquant 27.29, Centocor CA 19-9): As reported.
Description Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40kD and 68kD and isoelectric pH between 4.9-7.8. The individual cytokeratin polypeptides are designated 1 to 20. Cytokeratin 1 has the highest molecular weight and the highest isoelectric pH, while cytokeratin 19 has the lowest molecular weight and a low isoelectric pH. The cytokeratins are divided into the type I and type II subgroups, the type II family members comprising the basic to neutral cytokeratins 1-8, while the type I group comprises the acidic cytokeratins 9-20. The cytokeratins are expressed in combinations which characterize the type of epithelium. Cytokeratin 19 is the smallest human cytokeratin (40kD) and is found in many simple and invariably in some non-keratinizing stratified squamous epithelia. All adenocarcinomas tested have been positive for cytokeratin 19. Known Contaminants (RIA): Elecsys CA-125: As Reported Elecsys 15-3 Assay: As Reported Elecsys CA 19-9: As Reported Concentration: Specific Protein: As Reported Total Protein: As Reported Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.