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Categories: Peptides & Proteins / Proteins

Product name			Artocarpus integrifolia (AIA)
Catalog No			USB-518232
Supplier’s Catalog No			518232
Supplier			US Biologicals
Source antigen			Jacalin
Reactivity
Cross reactivity
Applications
Molecular weight			66

Storage			-20°C
Other names
Grade			Affinity Purified
Purity			Affinity purified
Form			Supplied as a lyophilized powder.
Reactivity life			2 years
Note			For reserch purpose only
Purity			Affinity purified
Description			Jacalin lectin (AIA) is purified by affinity chromatography and is tetrameric two-chain structure consisting of four identical protomers with an isoelectric point of pH 7.8. The lectin has specificity for blood group types O (+SA) and T. Jacalin is considered a galactose-specific lectin and elutes with galactose or melibiose. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N terminus of the alpha; -chain. The protein’s structure explains it’s carbohydrate-binding specificity of T-antigen disaccharide Galβ1,3GalNAc. Potent inhibitors of jacalin include D-galactose, β-Met-Gal and 2-deoxy-alpha; -D-galactose. Source: Jacalin Blood Specificity: O (+SA), T antigen Sugar Specificity: Galbeta; 3GalNAc Inhibitory Carbohydrate: Galactose or Melibiose Divalent Ions: None Required Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.