Galanthus nivalis (Snowdrop bulb) (GNA)

Catalog No : USB-G1044
298.86€
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Product name Galanthus nivalis (Snowdrop bulb) (GNA)
Catalog No USB-G1044
Supplier’s Catalog No G1044
Supplier US Biologicals
Source antigen Galanthus nivalis (snowdrop bulb)
Reactivity
Cross reactivity
Applications
Molecular weight 263044
Storage -20°C
Other names
Grade Molecular Biology Grade
Purity Highly purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.
Form Supplied as a lyophilized powder from PBS, pH 7.3. Reconstitute with sterile PBS, 0.09% sodium azide.
Reactivity life 12 months
Note For reserch purpose only
Purity Highly purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.
Description Galanthus nivalis agglutinin (GNA) is a small molecular weight tetramer consisting of subunits of about 13,000D. This lectin contains little or no carbohydrate. Unlike most mannose-specific lectins, it is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be preferentially directed toward structures containing (a-1,3) mannose residues. In contrast to most mannose-binding lectins, GNA will not bind alpha linked glucose. Reports indicate that this lectin binds IgM, but not bind IgG immunoglobulin classes of rat and mouse. The only protein from human serum reported to bind to this lectin is a2-macroglobulin. Isoelectric Point: < pH 4.6 Activity (unconjugated): ≤ 15ug/ml will agglutinate human type O erythrocytes. Carbohydrate Specificity: Mannose Inhibitory Carbohydrate: Mannose a-1,3-mannose Mannose (> 0.2M ) Inhibiting/Eluting Sugar: 100mM-200mM a-methyl mannoside Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS, 0.1% sodium azide. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.