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Categories: Peptides & Proteins / Proteins

Product name			Galanthus nivalis (Snowdrop bulb) (GNA) (Agarose)
Catalog No			USB-G1044-05
Supplier’s Catalog No			G1044-05
Supplier			US Biologicals
Source antigen			Galanthus nivalis (snowdrop bulb)
Reactivity
Cross reactivity
Applications
Molecular weight			263044

Storage			4°C Do Not Freeze
Other names
Grade			Molecular Biology Grade
Purity			Purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.
Form			Supplied as a liquid in PBS, pH 7.3. 0.05% sodium azide. Labeled with Agarose.
Reactivity life			12 months
Note			For reserch purpose only
Purity			Purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.
Description			Galanthus nivalis agglutinin (GNA) is a small molecular weight tetramer consisting of subunits of about 13,000D. This lectin contains little or no carbohydrate. Unlike most mannose-specific lectins, it is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be preferentially directed toward structures containing (a-1,3) mannose residues. In contrast to most mannose-binding lectins, GNA will not bind alpha linked glucose. Reports indicate that this lectin binds IgM, but not bind IgG immunoglobulin classes of rat and mouse. The only protein from human serum reported to bind to this lectin is a2-macroglobulin. Activity (unconjugated): ≤15mg/ml will agglutinate human type O erythrocytes. Carbohydrate Specificity: Mannose Inhibitory Carbohydrate: Mannose a-1,3-mannose, Mannose (>0.2M ) Inhibiting/Eluting Sugar: 100mM-200mM a-methyl mannoside Storage and Stability: Stored at 4°C only. Do not freeze. Stable for at least 6 months at 4°C. For maximum recovery of product, centrifuge prior to removing the cap. Further dilutions can be made in assay buffer.