Galanthus nivalis (Snowdrop bulb) (GNA) (Biotin)

Catalog No : USB-G1044-15
377.02€
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Product name Galanthus nivalis (Snowdrop bulb) (GNA) (Biotin)
Catalog No USB-G1044-15
Supplier’s Catalog No G1044-15
Supplier US Biologicals
Source antigen Galanthus nivalis (snowdrop bulb)
Reactivity
Cross reactivity
Applications
Molecular weight 263044
Storage -20°C
Other names
Grade Molecular Biology Grade
Purity Highly purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.
Form Supplied as a liquid in PBS, pH 7.2-7.4. Labeled with Biotin.
Reactivity life 12 months
Note For reserch purpose only
Purity Highly purified. Three bands at 26kD, 30kD and 44kD detected by SDS-PAGE.
Description Galanthus nivalis agglutinin (GNA) is a small molecular weight tetramer consisting of subunits of about 13,000D. This lectin contains little or no carbohydrate. Unlike most mannose-specific lectins, it is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be preferentially directed toward structures containing (a-1,3) mannose residues. In contrast to most mannose-binding lectins, GNA will not bind alpha linked glucose. Reports indicate that this lectin binds IgM, but not bind IgG immunoglobulin classes of rat and mouse. The only protein from human serum reported to bind to this lectin is a2-macroglobulin. Activity (unconjugated): ≤ 15ug/ml will agglutinate human type O erythrocytes. Isoelectric Point: < pH 4.6 Carbohydrate Specificity: Mannose Inhibitory Carbohydrate: Mannose a-1,3-mannose Mannose (> 0.2M ) Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.