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Categories: Peptides & Proteins / Proteins

Product name			Galanthus nivalis (Snowdrop bulb) (GNA) (HRP)
Catalog No			USB-G1044-25
Supplier’s Catalog No			G1044-25
Supplier			US Biologicals
Source antigen			Galanthus nivalis (snowdrop bulb)
Reactivity
Cross reactivity
Applications
Molecular weight			263044

Storage			-20°C
Other names
Grade			Purified
Purity			Purified
Form			Supplied as a liquid in PBS, pH 7.3. Labeled with horseradish peroxidase (HRP).
Reactivity life			12 months
Note			For reserch purpose only
Purity			Purified
Description			Galanthus nivalis agglutinin (GNA) is a small molecular weight tetramer consisting of subunits of about 13,000D. This lectin contains little or no carbohydrate. Unlike most mannose-specific lectins, it is not a metalloprotein and does not require Ca++ or Mn++ for binding. Binding seems to be preferentially directed toward structures containing (a-1,3) mannose residues. In contrast to most mannose-binding lectins, GNA will not bind alpha linked glucose. Reports indicate that this lectin binds IgM, but not bind IgG immunoglobulin classes of rat and mouse. The only protein from human serum reported to bind to this lectin is a2-macroglobulin. Activity (unconjugated): ≤15ug/ml will agglutinate human type O erythrocytes. Carbohydrate Specificity: Mannose Inhibitory Carbohydrate: Mannose alpha(1,3) >Mannose Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Labeled with horseradish peroxidase (HRP). Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. HRP conjugates are sensitive to light.