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Categories: Peptides & Proteins / Proteins

Product name			TIMP1, Recombinant, Human, aa24-207, His-Tag (TIMP metalloproteinase inhibitor 1, CLGI, EPA, EPO, HCI, TIMP)
Catalog No			USB-351522
Supplier’s Catalog No			351522
Supplier			US Biologicals
Source antigen			Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight			21.5

Storage			-20°C/-70°C
Other names
Grade			Purified
Purity			~90% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4. No preservative added.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~90% (SDS-PAGE)
Description			TIMP1, also known as TIMP metalloproteinase inhibitor 1, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function Source: Recombinant protein corresponding to aa24-207 from human TIPM1, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~21.5kD (190aa) AA Sequence: CTCVPPHPQT AFCNSDLVIR AKFVGTPEVN QTTLYQRYEI KMTKMYKGFQ ALGDAADIRF VYTPAMESVC GYFHRSHNRS EEFLIAGKLQ DGLLHITTCS FVAPWNSLSL AQRRGFTKTY TVGCEECTVF PCLSIPCKLQ SGTHCLWTDQ LLQGSEKGFQ SRHLACLPRE PGLCTWQSLR SQIAHHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.