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Categories: Peptides & Proteins / Proteins

Product name			TIMP1, Recombinant, Mouse, aa25-205, His-Tag (Metalloproteinase inhibitor 1, Timp1, Clgi, EPA, Timp, TIMP-1, TPA-S1)
Catalog No			USB-351523
Supplier’s Catalog No			351523
Supplier			US Biologicals
Source antigen			Recombinant, mouse from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight			21

Storage			-20°C/-70°C
Other names
Grade			Highly Purified
Purity			~95% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			12 months
Note			For reserch purpose only
Purity			~95% (SDS-PAGE)
Description			TIMP1, also known as metalloproteinase inhibitor 1, is a member of the TIMP family. Tissue inhibitors of metalloproteinases (TIMP) family are natural inhibitors of the matrix metalloproteinases (MMPs), the zinc enzymes involved in extracellular matrix maintenance and remodeling. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. It has been identified as a multifunctional molecule with divergent functions. Source: Recombinant protein corresponding to aa25-205 from mouse TIMP1, fused to His-tag at C-terminal expressed in insect cell. Molecular Weight: ~21kD (187aa) AA Sequence: CSCAPPHPQT AFCNSDLVIR AKFMGSPEIN ETTLYQRYKI KMTKMLKGFK AVGNAADIRY AYTPVMESLC GYAHKSQNRS EEFLITGRLR NGNLHISACS FLVPWRTLSP AQQRAFSKTY SAGCGVCTVF PCLSIPCKLE SDTHCLWTDQ VLVGSEDYQS RHFACLPRNP GLCTWRSLGA RHHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.