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Categories: Peptides & Proteins / Proteins

Product name			TIMP4, Recombinant, Human, aa30-224, His-Tag (Metalloproteinase inhibitor 4)
Catalog No			USB-369138
Supplier’s Catalog No			369138
Supplier			US Biologicals
Source antigen			Recombinant, human from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight			23.5

Storage			-20°C
Other names
Grade			Highly Purified
Purity			~90% (SDS-PAGE)
Form			Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~90% (SDS-PAGE)
Description			TIMP4, as known as metalloproteinase inhibitor 4, is a family of secreted protein that regulates the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases. There are four known members of the family, TIMP1, 2, 3 and 4. TIMP4 is produced by a wide range of tissues, particularly brain, heart, ovary and skeletal muscle. Limited studies have shown that this protein has a tumor suppressive effect against Wilm s tumor, exhibits negative correlation with glioma malignancy and is found in breast carcinoma cells. Source: Recombinant protein corresponding to aa30-224 from human TIMP4, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~23.5kD (204aa) 18-28kD (SDS-PAGE under reducing conditions) Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.