SDC2, Recombinant, Human, aa19-144, His-Tag (Syndecan 2, CD362, HSPG, HSPG1, SYND2)

Catalog No : USB-377962
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Product name SDC2, Recombinant, Human, aa19-144, His-Tag (Syndecan 2, CD362, HSPG, HSPG1, SYND2)
Catalog No USB-377962
Supplier’s Catalog No 377962
Supplier US Biologicals
Source antigen Recombinant, Baculovirus
Reactivity
Cross reactivity
Applications
Molecular weight 15
Storage -20°C
Other names
Grade Highly Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description SDC2, also known as syndecan 2, is a conserved family of heparan- and chondroitin-sulfate carrying transmembrane protein. It is a cell membrane proteoglycans that can modulate the activity and dynamics of some growth factor receptors and integrins. It is expressed in hepatic stellate cells (HSCs), a key cell type involved in matrix deposition in liver fibrotic disorders. It has been implicated in the formation of specialized membrane domains and functions as a direct link between the extracellular environment and the organization of the cortical cytoplasm. Source: Recombinant protein corresponding to aa19-144 from human SDC2, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~15kD (135aa), 18-28kD (SDS-PAGE under reducing conditions) Endotoxin: <1EU/1ug (determined by LAL method) AA Sequence: ADPESRAELT SDKDMYLDNS SIEEASGVYP IDDDDYASAS GSGADEDVES PELTTSRPLP KILLTSAAPK VETTTLNIQN KIPAQTKSPE ETDKEKVHLS DSERKMDPAE EDTNVYTEKH SDSLFKRTEH HHHHH Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.