MHC class I polypeptide-related sequence B, active (MICB), Recombinant, Human
Catalog No : USB-348177
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| Product name | MHC class I polypeptide-related sequence B, active (MICB), Recombinant, Human | ||
|---|---|---|---|
| Catalog No | USB-348177 | ||
| Supplier’s Catalog No | 348177 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 32.8 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥95% as determined by SDS-PAGE and HPLC. | ||
| Form | Lyophilized from 0.2um filtered 20mM Tris, 150mM NaCl, pH 8.0 | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥95% as determined by SDS-PAGE and HPLC. | ||
| Description | Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. {ECO:0000269|PubMed:11491531, ECO:0000269|PubMed:11777960, ECO:0000269|PubMed:9497295}. Biological Activity: Fully biologically active when compared to standard. The specific activity is determined by binding MICB antibody in ELISA. Sequence: AEPHSLRYNL MVLSQDESVQ SGFLAEGHLD GQPFLRYDRQ KRRAKPQGQW AEDVLGAKTW DTETEDLTEN GQDLRRTLTH IKDQKGGLHS LQEIRVCEIH EDSSTRGSRH FYYDGELFLS QNLETQESTV PQSSRAQTLA MNVTNFWKED AMKTKTHYRA MQADCLQKLQ RYLKSGVAIR RTVPPMVNVT CSEVSEGNIT VTCRASSFYP RNITLTWRQD GVSLSHNTQQ WGDVLPDGNG TYQTWVATRI RQGEEQRFTC YMEHSGNHGT HPVPSGKVLV LQSQRTD Molecular Weight: 32.8kD PubMed ID: 8575823; 8952966; 17678727; 14702039; 14574404; 15489334; 8995188; 9271635; 15191526; 9694358; 9321430; 10746790; 15304008; 9497295; 10e359807; 11287116; 11239445; 11491531; 12466900; 11777960; 12569559; 12782710; 12538683; 16698441; 16849432; 17565371; 17003176; 17561376; 17641203; 18395517; 12133964 Gene Name: MICB, PERB11.2 Swiss Prot: Q29980 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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