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Categories: Peptides & Proteins / Proteins

Product name			CHCHD3, Recombinant, Human, aa1-227, His-Tag (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing Protein 3)
Catalog No			USB-218032
Supplier’s Catalog No			218032
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			28.5

Storage			-20°C
Other names
Grade			Purified
Purity			~80% (SDS-PAGE)
Form			Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.2M sodium chloride, 2mM DTT, 50% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			~80% (SDS-PAGE)
Description			Coiled-coil-helix-coiled-coil-helix domain containing protein 3, also known as CHCHD3, is required for maintenance of mitochondrial crista integrity and mitochondrial function. This protein may act as a scaffolding protein that stabilizes protein complexes involved in crista architecture and protein import. It has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Source: Recombinant protein corresponding to aa1-227 from human CHCHD3, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~28.5kD (250aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.