Imugex

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Categories: Peptides & Proteins / Proteins

Product name			ABCA1, Control Peptide (ABC 1, ABC Transporter 1, ATP-binding Cassette 1 , ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, HDLDT1, TGD)
Catalog No			USB-A0004A
Supplier’s Catalog No			A0004A
Supplier			US Biologicals
Source antigen			Human synthetic peptide
Reactivity
Cross reactivity			Human,
Applications
Molecular weight

Storage			-70°C
Other names
Grade			Purified
Purity			Purified
Form			Supplied as a liquid in ddH2O. No preservative added.
Reactivity life			12 months
Note			For reserch purpose only
Purity			Purified
Description			Partial peptide sequence somewhere between amino acids 1100-1300 of the human ABCA1 gene. Control Peptide for A0004. Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. Applications: Suitable for use in ELISA and Antibody Blocking. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.