Fumitremorgin C (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a­-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5­H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-­b]indole-5,14-dione)

Catalog No : USB-145674
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Product name Fumitremorgin C (5aS,12S,14aS)-1,2,3,5a,6,11,12,14a­-Octahydro-9-methoxy-12-(2-methyl-1-propen-1-yl)-5­H,14H-pyrrolo[1'',2'':4',5']pyrazino[1',2':1,6]pyrido[3,4-­b]indole-5,14-dione)
Catalog No USB-145674
Supplier’s Catalog No 145674
Supplier US Biologicals
Source antigen
Reactivity
Cross reactivity
Applications
Molecular weight 379.45
Storage 4°C
Other names
Grade Highly Purified
Purity ~98% (HPLC)
Form Supplied as an off-white lyophilized solid.
Reactivity life 12 months
Note For reserch purpose only
Purity ~98% (HPLC)
Description Inhibitor of BCRP-mediated multidrug resistance. Chemosensitizing agent; selectively reverses BCRP-mediated multidrug resistance to mitoxantrone, doxorubicin and topotecan in transfected MCF-7 cells. Does not reverse resistance in P-gp- or MRP-positive cells. Sequence: C22H25N3O3 Solubility: DMSO (~10mM) Molecular Weight: ~379.45 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.