Imugex

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Categories: Peptides & Proteins / Proteins

Product name			Myelin Basic Protein, (4-14), phosphorylated (pGlu4)
Catalog No			USB-M9758-03L
Supplier’s Catalog No			M9758-03L
Supplier			US Biologicals
Source antigen			Synthetic peptide
Reactivity
Cross reactivity
Applications
Molecular weight			1374

Storage			-20°C
Other names
Grade			Highly Purified
Purity			95+% HPLC, Mass Spec
Form			Supplied as a white to off-white lyophilized powder.
Reactivity life			12 months
Note			For reserch purpose only
Purity			95+% HPLC, Mass Spec
Description			Myelin basic protein (MBP) is a single-chain, flexible polypeptide of about 18.5kD existing in its natural environment as an extrinsic and loosely bound component of the cytoplasmic portion of the myelin membrane sandwich. Ultrastructural immunocytochemistry with anti-myelin basic protein has shown that MBP is localized in the compact myelin sheath. MBP has not been demonstrated in rough endoplasmic reticulum, lysosomes or any other cytoplasmic organelles (3). MBP serves as a marker for oligodendrocytes and Schwann cells (3). MBP is also a marker for malignant schwannomas (4) and appears to play a significant role in the etiology of multiple sclerosis (5–7) and experimental autoimmune encephalomyelitis (8). Selective protein kinase C (PKC) substrate Sequence (linear): pGlu-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH Amino Acid Analysis: Confirms expected sequence Peptide Content: 81.2 ± 4% Solubility: H2O Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.