Myosin Light Chain 2, aa1-166, His-Tag, Recombinant, Human (MYL2, MLC2, CMH10)

Catalog No : USB-M9848-03J
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Product name Myosin Light Chain 2, aa1-166, His-Tag, Recombinant, Human (MYL2, MLC2, CMH10)
Catalog No USB-M9848-03J
Supplier’s Catalog No M9848-03J
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 20.9
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% by SDS PAGE. Purified by using conventional chromatography techniques.
Form Supplied as a liquid in 20mM Tris pH 8.0, 20% glycerol, 5mM CaCl2.
Reactivity life 6 months
Note For reserch purpose only
Purity ~95% by SDS PAGE. Purified by using conventional chromatography techniques.
Description Myosin, light chain 2 (MYL2) encodes the regulatory light chain associated with cardiac myosin beta heavy chain. It is an important protein involved in the regulation of myosin ATPase activity in smooth muscle and Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAPKKAKKRA GGANSNVFSM FEQTQIQEFK EAFTIMDQNR DGFIDKNDLR DTFAALGRVN VKNEEIDEMI KEAPGPINFT VFLTMFGEKL KGADPEETIL NAFKVFDPEG KGVLKADYVR EMLTTQAERF SKEEVDQMFA AFPPDVTGNL DYKNLVHIIT HGEEKD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.