PTX3, Mouse, Control Peptide (Long Pentraxin, TSG14)

Catalog No : USB-P9183-04C
417.25€
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Product name PTX3, Mouse, Control Peptide (Long Pentraxin, TSG14)
Catalog No USB-P9183-04C
Supplier’s Catalog No P9183-04C
Supplier US Biologicals
Source antigen Mouse synthetic peptide
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Purified
Purity Purified
Form Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Reactivity life 12 months
Note For reserch purpose only
Purity Purified
Description Pentraxins are a family of proteins emerging from genes that are conserved in their carboxy-terminal halves a pentraxin domain  and are prototypical acute phase proteins with acquired novel amino-terminal domains. Pentraxins, include C reactive protein (CRP) and Serum Amyloid P component (SAP), which serve as indicators of inflammatory reactions as a result of the exposure of liver cells to cytokines, mainly interleukin-6 (IL-6). PTX3 or TSG14 or long pentraxin (human mature chain 364 aa, chromosome 3q25; ~43 kda ) is structurally related but different form classic pentraxins.  PTX3 was clones as an IL-1 inducible gene in endothelial cells, and as TNF-inducible gene in fibroblasts called TSG14.  The C-terminal half of PTX3 aligns with CRP and SAP, but the N-terminal half is unique.  PTX3 is induced by LPS, IL-1 and TNF-alpha, but not IL-6.  During an acute phase response induced by LPS, PTX3 is expressed in many organs (heart, skeletal muscle).  PTX3 expression may be indicative of its role in cardiovascular and inflammatory pathology. Source: 16aa peptide from Mouse PTX3 (1) Location: ~N-terminus Species Sequence Homology: Human-93%. Applications: Suitable for use in ELISA as a control peptide for P9183-04B. Other applications not tested. Recommended Dilution: ELISA: Coat ELISA plates at 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.