GAS7b, Recombinant, Human (Growth Arrest-specific 7, Isoform b)

Catalog No : USB-G2016-07A
490.82€
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Product name GAS7b, Recombinant, Human (Growth Arrest-specific 7, Isoform b)
Catalog No USB-G2016-07A
Supplier’s Catalog No G2016-07A
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 49.8
Storage -20°C
Other names
Grade Highly Purified
Purity ≥95% by SDS-PAGE
Form Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, 100mM NaCl, 2mM DTT, 10% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ≥95% by SDS-PAGE
Description Growth arrest-specific 7, also known as GAS7, is expressed primarily in terminally differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 plays a putative role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Inhibition of GAS7 production in terminally differentiating cultures of embryonic murine cerebellum impedes neurite outgrowth. Conversely, the hyper-expression of GAS7 may play an important role in the initiation and development of human osteosarcoma. Source: Recombinant GAS7, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: 49.8kD (436 aa) Endotoxin Level: ≤1.0 EU /1ug of protein (LAL). AA Sequence: MGSSHHHHHH SSGLVPRGSH MKPGMVPPPP GEESQTVILP PGWQSYLSPQ GRRYYVNTTT NETTWERPSS SPGIPASPGS HRSSLPPTVN GYHASGTPAH PPETAHMSVR KSTGDSQNLG SSSPSKKQSK ENTITINCVT FPHPDTMPEQ QLLKPTEWSY CDYFWADKKD PQGNGTVAGF ELLLQKQLKG KQMQKEMSEF IRERIKIEED YAKNLAKLSQ NSLASQEEGS LGEAWAQVKK SLADEAEVHL KFSAKLHSEV EKPLMNFREN FKKDMKKCDH HIADLRKQLA SRYASVEKAR KALTERQRDL EMKTQQLEIK LSNKTEEDIK KARRKSTQAG DDLMRCVDLY NQAQSKWFEE MVTTTLELER LEVERVEMIR QHLCQYTQLR HETDMFNQST VEPVDQLLRK VDPAKDRELW VREHKTGNIR PVDMEI Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.