GFR alpha3, IN, Blocking Peptide (Glycosylphosphadidylinositol linked Protein, GDNFRg, Ret ligand 3, RETL3)
Catalog No : USB-G2033-50P
367.83€
0.00€
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| Product name | GFR alpha3, IN, Blocking Peptide (Glycosylphosphadidylinositol linked Protein, GDNFRg, Ret ligand 3, RETL3) | ||
|---|---|---|---|
| Catalog No | USB-G2033-50P | ||
| Supplier’s Catalog No | G2033-50P | ||
| Supplier | US Biologicals | ||
| Source antigen | Synthetic peptide | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | Purified 60-70% | ||
| Form | Supplied as a lyophilized powder. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | Purified 60-70% | ||
| Description | Peptide corresponding to amino acids from 347 to 360 of murine GFRa-3 (6). Blocking peptide for catalog number: G2033-50. Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin (1). Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRa and Ret receptor tyrosine kinase GFRb (2). Following the findings of GFRa-1 and -2, a novel receptor in GFRa family was identified very recently from human and mouse and designated GFRa-3 (3-7). GFRa-3 binds persephin, thus, persephin, GFRa-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function. | ||
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