NTF4, Recombinant, Human (NT-4, Neurotrophin-5, NT-5, Neutrophic Factor 4, NTF5, Neurotrophin-4)
Catalog No : USB-500321
456.33€
0.00€
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| Product name | NTF4, Recombinant, Human (NT-4, Neurotrophin-5, NT-5, Neutrophic Factor 4, NTF5, Neurotrophin-4) | ||
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| Catalog No | USB-500321 | ||
| Supplier’s Catalog No | 500321 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 14 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder in PBS, pH 7.5. Reconstitute with sterile ddH2O to 0.1mg/ml. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | Neurotrophins are well-known retrograde signaling molecules that regulate differentiation and cell survival in many central and peripheral neurons. Neurotrophin-4 (NT-4) is the most recently discovered neurotrophic factor in mammals and, functionally, the least well understood. Little is known about the role of NT-4 in supporting the survival of identified classes of sensory neurons. Currently, the only available data are from cell counts of whole sensory ganglia. Mice lacking NT-4 (NT-4/) exhibit a loss of ~50% of the neurons in the nodose-petrosal and geniculate ganglia but no apparent loss of neurons in the dorsal root ganglia. Source: Recombinant protein corresponding to human NTF4 expressed in E. coli. Molecular Weight: ~14kD Biological Activity: The ED50 was determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures, and was 10-50ng/mL. Endotoxin: <1EU/ug (LAL) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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