Ac-Arg-Leu-Arg-AMC (Ac-RLR-AMC, Proteasome Substrate)
Catalog No : USB-226820
374.72€
0.00€
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| Product name | Ac-Arg-Leu-Arg-AMC (Ac-RLR-AMC, Proteasome Substrate) | ||
|---|---|---|---|
| Catalog No | USB-226820 | ||
| Supplier’s Catalog No | 226820 | ||
| Supplier | US Biologicals | ||
| Source antigen | Synthetic | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 642.8 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥97% (HPLC) | ||
| Form | Supplied as a solid lyophilized powder. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Description | Fluorogenic tri-peptide substrate for measuring the trypsin-like peptidase activity of the 20S proteasome. It is cleaved exclusively at the amide R-AMC bond to release fluorescent product. Shows low Km and high specific activity. This substrate is useful for inhibitor screening and kinetic analysis. Excitation: Excitation: 380nm. Emission: 460nm. Molecular Formula: C30H46N10O6 Molecular Weight: 642.8 Sequence: Acetyl-Arg-Leu-Arg-7-amido-4-methylcoumarin Solubility: Soluble in DMSO, methanol or water (aqueous solutions). Use: Add from DMSO stock directly to in vitro or in vivo assay at desired concentration. Typical concentrations range from 10-100uM. Activity with purified proteasome: Km=78uM. Storage and Stability: Stable for at least 1 year after receipt when stored at -20°C. | ||
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