DNER (Extracellular Domain), Recombinant, Mouse: Fc Human (BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor)

Catalog No : USB-044760
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Product name DNER (Extracellular Domain), Recombinant, Mouse: Fc Human (BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor)
Catalog No USB-044760
Supplier’s Catalog No 044760
Supplier US Biologicals
Source antigen Recombinant, HEK 293 cells
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Purified
Purity ≥85% (SDS-PAGE)
Form Supplied as a liquid from a 0.2um-filtered solution in PBS. No preservative added.
Reactivity life 6 months
Note For reserch purpose only
Purity ≥85% (SDS-PAGE)
Description DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis. Sequence: Signal peptide and extracellular domain of mouse DNER (aa1-640) are fused at the C-terminus to the Fc portion of human IgG, expressed in HEK 293 cells. Endotoxin: <0.1EU/ug (LAL test; Lonza) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.