Jagged-2,Fc, Recombinant, Human (Protein Jagged-2, hJ2, JAG2)
Catalog No : USB-044972
487.37€
0.00€
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| Product name | Jagged-2,Fc, Recombinant, Human (Protein Jagged-2, hJ2, JAG2) | ||
|---|---|---|---|
| Catalog No | USB-044972 | ||
| Supplier’s Catalog No | 044972 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Human, HEK 293 cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 150 | ||
| Storage | 4°C/-20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | >90% (SDS-PAGE) | ||
| Form | Supplied as a liquid from a 0.2um-filtered solution in PBS, pH 7.2. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >90% (SDS-PAGE) | ||
| Description | Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development. Sequence: Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG. Storage and Stability: Short-term Storage: +4°C Long-term Storage: -20°C Working aliquots are stable for up to 3 months when stored at -20°C. | ||
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