Leptin, Triple Antagonist (tA), Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, Ob, Obese Protein, Obesity, Obesity Factor, Obesity Homolog Mouse, OBS)
Catalog No : USB-L1670-15C1
419.55€
0.00€
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| Product name | Leptin, Triple Antagonist (tA), Recombinant, Human (LEP, Leptin Mouse Obesity Homolog, Leptin Precursor Obesity Factor, Ob, Obese Protein, Obesity, Obesity Factor, Obesity Homolog Mouse, OBS) | ||
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| Catalog No | USB-L1670-15C1 | ||
| Supplier’s Catalog No | L1670-15C1 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 16 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥ 98.0% as determined by RP-HPLC or SDS-PAGE. | ||
| Form | Supplied as lyophilized powder from a concentrated 1mg/ml solution with NaHCO3. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥ 98.0% as determined by RP-HPLC or SDS-PAGE. | ||
| Description | Leptin Antagonist Triple Mutant Human Recombinant is a single non-glycosilated polypeptide chain containing 146 amino and additional Ala at N-terminus acids and having a molecular weight of 16kD. Leptin was mutated, resulting in L39A/D40A/F41A. Leptin Antagonist Triple Mutant Human Recombinant was purified by proprietary chromatographic techniques Source: Stem cell factor Leptin Human Recombinant expressed in E. coli. Amino Acid Sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Gln. Protein Content: Protein quantitation was carried out by UV spectroscopy at 280 nm using the absorbency value of 0.88 as the extinction coefficient for a 0.1% (1mg/ml) solution at pH 8.0. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). Biological Activity: Leptin triple antagonist is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of human leptin receptor. It also inhibits various leptin effects in several in vitro bioassays. Storage and Stability: Lyophilized Leptin protein although stable at room temperature for 3 weeks, should be stored desiccated below -20°C. Upon reconstitution IL6 should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze-thaw cycles. | ||
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