gAcrp30, Recombinant, Human (Globular Adipocyte Complement-related Protein of 30kD, apm-1, Adipolean)

Catalog No : USB-G1016-02B
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Product name gAcrp30, Recombinant, Human (Globular Adipocyte Complement-related Protein of 30kD, apm-1, Adipolean)
Catalog No USB-G1016-02B
Supplier’s Catalog No G1016-02B
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Highly Purified
Purity ≥ 98% by SDS-PAGE and HPLC. Endotoxin: ≤ 0.1ng/ug (1EU/ug).
Form Supplied as a lyophilized powder. Reconstitute with sterile dH2O.
Reactivity life 6 months
Note For reserch purpose only
Purity ≥ 98% by SDS-PAGE and HPLC. Endotoxin: ≤ 0.1ng/ug (1EU/ug).
Description gAcrp30 is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, gAcrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. Recombinant human gAcrp30/Adipolean is a 16.6kD protein consisting of 145 amino acid residues. Biological Activity:Determined by its ability to inhibit the proliferation of murine myeloid cell lines M1. The ED50 for this effect is 1.0-3.0ug/ml. Endotoxin: ≤ 0.1ng/ug (1EU/ug) Form: Supplied as a lyophilized powder. AA Sequence: MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile buffer. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Country of Origin: USA