ERBB3, Recombinant, Mouse, aa20-641, His-Tag (C76256, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, Erbb-3, Erbb3r, Her3)

Catalog No : USB-351212
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Product name ERBB3, Recombinant, Mouse, aa20-641, His-Tag (C76256, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 3 avian, Erbb-3, Erbb3r, Her3)
Catalog No USB-351212
Supplier’s Catalog No 351212
Supplier US Biologicals
Source antigen Recombinant, mouse from insect cell line
Reactivity
Cross reactivity
Applications
Molecular weight 69.5
Storage -20°C/-70°C
Other names
Grade Purified
Purity ~90% (SDS-PAGE)
Form Supplied as a liquid in PBS, pH 7.4, 10% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity ~90% (SDS-PAGE)
Description ERBB3, also known as receptor tyrosine-protein kinase erbB-3, is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This protein has been shown to implicate in numerous cancers, including prostate, bladder, and breast tumors. Also, it is found in epithelial cell layers of gastrointestinal, reproductive, urinary, endocrine and nervous systems, skin and muscle. ERBB3 has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form. Source: Recombinant protein corresponding to aa20-641 from mouse ERBB3, fused to His-tag at C-terminal expressed in Insect cell. Molecular Weight: ~69.5kD (630aa) AA Sequence: SEMGNSQAVC PGTLNGLSVT GDADNQYQTL YKLYEKCEVV MGNLEIVLTG HNADLSFLQW IREVTGYVLV AMNEFSVLPL PNLRVVRGTQ VYDGKFAIFV MLNYNTNSSH ALRQLRFTQL TEILLGGVYI EKNDKLCHMD TIDWRDIVRV PDAEIVVKNN GGNCPPCHEV CKGRCWGPGP EDCQILTKTI CAPQCNGRCF GPNPNQCCHD ECAGGCSGPQ DTDCFACRHF NDSGACVPRC PAPLVYNKLT FQLEPNPHIK YQYGGVCVAS CPHNFVVDQT FCVRACPADK MEVDKNGLKM CEPCRGLCPK ACEGTGSGSR YQTVDSSNID GFVNCTKILG NLDFLITGLN GDPWHKIPAL DPEKLNVFRT VREITGYLNI QSWPPHMHNF SVFSNLTTIG GRSLYNRGFS LLIMKNLNVT SLGFRSLKEI SAGRVYISAN QQLCYHHSLN WTRLLRGPAE ERLDIKYNRP LGECVAEGKV CDPLCSSGGC WGPGPGQCLS CRNYSREGVC VTHCNVLQGE PREFVHEAHC FSCHPECQPM EGTSTCNGSG SDACARCAHF RDGPHCVNSC PHGILGAKGP IYKYPDAQNE CRPCHENCTQ GCKGPELQDC LGQAEVLMSK PHLEHHHHHH Endotoxin: ~1EU/1ug (LAL) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.