ABL1, Recombinant, Human, His-Tag (ABL, JTK7, p150, c-ABL, v-abl, bcr/abl)
Catalog No : USB-499759
572.43€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | ABL1, Recombinant, Human, His-Tag (ABL, JTK7, p150, c-ABL, v-abl, bcr/abl) | ||
|---|---|---|---|
| Catalog No | USB-499759 | ||
| Supplier’s Catalog No | 499759 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Insect cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 135 | ||
| Storage | -70°C | ||
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| Other names | |||
| Grade | Purified | ||
| Purity | Purified (~70-90%) | ||
| Form | Supplied as a liquid in 50mM sodium phosphate, pH 7.0, 300mM sodium chloride, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | Purified (~70-90%) | ||
| Description | ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene. Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1. Source: Recombinant protein corresponding to human ABL1, fused to His-Tag at N-terminal, expressed in Insect cells. Molecular Weight: ~135kD Specific Activity: 871nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | ||
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