Opioid Receptor, kappa, NT (OPRK1, Opioid Receptor, kappa 1, Kappa-type Opioid Receptor, KOR, KOR-1, OPRK)

Catalog No : USB-O7030-34M
564.38€
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Product name Opioid Receptor, kappa, NT (OPRK1, Opioid Receptor, kappa 1, Kappa-type Opioid Receptor, KOR, KOR-1, OPRK)
Catalog No USB-O7030-34M
Supplier’s Catalog No O7030-34M
Supplier US Biologicals
Source antigen
Reactivity
Cross reactivity
Applications
Molecular weight 1929
Storage -20°C
Other names
Grade Purified
Purity 95+% HPLC, Mass Spec
Form Supplied as a white to off-white lyophilized powder.
Reactivity life 12 months
Note For reserch purpose only
Purity 95+% HPLC, Mass Spec
Description Opioid receptors are G-protein coupled receptors. Although the function of k-opioid receptors is unclear, recent evidence indicates that activation of the k-opioid receptor opposes a variety of mu-opioid receptor mediated actions throughout the brain and spinal cord. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities. Sequence (linear): Ac-Ser-Arg-Glu-Lys-Asp-Arg-Asn-Leu-Arg-Arg-Ile-Thr-Lys-Leu-Cys-NH2 Amino Acid Analysis: Confirms expected sequence Peptide Content: 79.3 ± 4% Solubility: H2O Storage and Stability: Lyophilized powder may be stored at 4°C for short-term only. Stable for 12 months at -20°C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.