Imugex

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Categories: Peptides & Proteins / Proteins

Product name			Brain Natriuretic Peptide, Pro, NT, aa1-76, Recombinant, Human (NT-proBNP, N-terminal prohormone brain natriuretic peptide)
Catalog No			USB-B2702-03F
Supplier’s Catalog No			B2702-03F
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight

Storage			-70°C
Other names
Grade			Purified
Purity			≥95% pure (Tricine-SDS-PAGE, reducing conditions).
Form			Supplied as a liquid in PBS, pH 7.4. No preservatives added.
Reactivity life			6 months
Note			For reserch purpose only
Purity			≥95% pure (Tricine-SDS-PAGE, reducing conditions).
Description			In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134aa precursor (prepro-BNP), which is cleaved by proteases to form a 26aa "signal" peptide and a 108aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76aa amino-terminal NT-proBNP and biologically active 32aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure. Immunoreactivity is confirmed by reaction with monoclonal antibodies against different epitopes of NT-proBNP. Source: Recombinant human pro-Brain Natriuretic peptide, NT, expressed in E. coli. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 6 months.