Cell division cycle associated 8, Recombinant, Human, aa19-280, His-Tag (BOR, Borealin, BOREALIN, Cell division cycle-associated protein 8, Dasra-B, FLJ10468, FLJ12042, hDasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein)
Catalog No : USB-C2098-69D
1019.57€
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| Product name | Cell division cycle associated 8, Recombinant, Human, aa19-280, His-Tag (BOR, Borealin, BOREALIN, Cell division cycle-associated protein 8, Dasra-B, FLJ10468, FLJ12042, hDasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein) | ||
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| Catalog No | USB-C2098-69D | ||
| Supplier’s Catalog No | C2098-69D | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 31.6 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~90% (SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M sodium chloride, 1mM DTT, 1mM EDTA, 50% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% (SDS-PAGE) | ||
| Description | CDCA8, also known as Borealin, is a component of the chromosomal passenger complex (CPC). The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein may be required to direct the CPC to centromeric DNA. Deletion of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach. Source: Recombinant corresponding to aa19-280 from human CDCA8, fused to His-tag at N-terminus expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MRKLASFLKD FDREVEIRIK QIESDRQNLL KEVDNLYNIE ILRLPKALRE MNWLDYFALG GNKQALEEAA TADLDITEIN KLTAEAIQTP LKSAKTRKVI QVDEMIVEEE EEEENERKNL QTARVKRCPP SKKRTQSIQG KGKGKRSSRA NTVTPAVGRL EVSMVKPTPG LTPRFDSRVF KTPGLRTPAA GERIYNISGN GSPLADSKEI FLTVPVGGGE SLRLLASDLQ RHSIAQLDPE ALGNIKKLSN RLAQICSSIR THK Molecular Weight: ~31.6kD (283aa) confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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