Lipoprotein, Low Density, Oxidized, Human (LDL)

Catalog No : USB-L2601-10M
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Product name Lipoprotein, Low Density, Oxidized, Human (LDL)
Catalog No USB-L2601-10M
Supplier’s Catalog No L2601-10M
Supplier US Biologicals
Source antigen Human plasma
Reactivity
Cross reactivity
Applications
Molecular weight
Storage 4°C Do Not Freeze
Other names
Grade Purified
Purity Purified to homogeneity by ultra-centrifugation. Oxidized using 20uM cupric sulfate in PBS at 37ºC for 24 hours. Oxidation is terminated with excess EDTA. The level of oxidation is measured using TBARS (Thiobarbituric acid reactive substances) determination using a Malondialdehyde (MDA) standard.
Form Supplied as a liquid in PBS, 0.3mM EDTA.
Reactivity life 12 months
Note For reserch purpose only
Description Low density lipoprotein (LDL) oxidative modification is one of the major processes involved in atherosclerosis along with other degenerative disorders. Oxidised LDL is preferentially accumulated by macrophages which become so called "foam cells" within the atheromatous plaque and contributes to the accumulation of cholesterol, typical of atherosclerosis. Applications: Suitable for use in Functional Assays. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 4 weeks after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.