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Categories: Peptides & Proteins / Proteins

Product name			FLT1, Recombinant, Human, GST-Tag (Fms-Like Tyrosine Kinase 1, FLT, VEGFR1)
Catalog No			USB-500014
Supplier’s Catalog No			500014
Supplier			US Biologicals
Source antigen			Recombinant, Insect cells
Reactivity
Cross reactivity
Applications
Molecular weight			94

Storage			-70°C
Other names
Grade			Purified
Purity			Purified (~70-90%)
Form			Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life			6 months
Note			For reserch purpose only
Purity			Purified (~70-90%)
Description			FLT1, also known as fms-like tyrosine kinase 1, is a member of the VEGFR family and is related to the oncogene ROS. The tyrosine kinase activity of FLT1 has been shown to play a key role in control of cell proliferation and differentiation. FLT1 is a receptor for vascular endothelial growth factor (VEGF) and it has been observed that the ratio of FLT1 mRNA to VEGF mRNA correlates with tumor angiogenesis and prognosis in non-small cell lung cancers. In addition to the full-length receptor, FLT1 gene also encodes a soluble form of receptor due to alternative splicing. Both the full length and soluble form of FLT1 show strong binding affinity for VEGF. Source: Recombinant protein corresponding to human FLT1 fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~94kD Specific Activity: 35nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.