Adenosine A3 Receptor, Rabbit (A3R) (Control Peptide)
Catalog No : USB-A0869-70N
417.25€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | Adenosine A3 Receptor, Rabbit (A3R) (Control Peptide) | ||
|---|---|---|---|
| Catalog No | USB-A0869-70N | ||
| Supplier’s Catalog No | A0869-70N | ||
| Supplier | US Biologicals | ||
| Source antigen | Rabbit synthetic peptide | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | Highly purified | ||
| Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | Highly purified | ||
| Description | A 15 amino acid sequence corresponding to human A3R gene. 46% homology (7/15aa) with rat and 20% (3/15aa) with sheep A3R sequences. Adenosine deaminase (ADA; EC 3.54.4) catalyzes deamination of adenosine to inosine. ADA is found in primarily cytosolic. It has also been located at the cell membrane and implicated in the control of the extracellular concentration of adenosine. The purine nucleoside adenosine modulates diverse physiological functions including induction of sedation, vasodilatation, suppression of cardiac rate and contractility, neurotransmitter release, inhibition of platelet aggregation and lipolysis. Adenosine released from cells interacts with membrane receptors (adenosine receptors, ARs). Based upon, biochemical and pharmacological criteria, ARs have been classified into A1, A2a, A2b, and A3. The high affinity receptor A1 inhibits adenyl cyclase, whereas low affinity receptor A2a stimulates the cyclase via G proteins. A2a receptor is believed to cause vasorelaxation in coronary artery. Various, ARs and their subtypes have recently been cloned from several species. ARs belong to the superfamily of G-protein coupled receptors and predicted to contain 7 transmembrane domains. The N-termini are predicted to be extracellular and the C-termini cytoplasmic. There is an overall 30% homology among the four ARs. ARs are distributed throughout the body. Gene location of various ARs: A1 (Chromosome 1; q.31.3-32.2); A2a (Chromosome 22); A2b (Chromosome 17; p.11.2-12); A3 (Chromos.1). | ||
Product Details
© 2020 Imugex All Rights Reserved