Dopamine Receptor, D4, Human, Control Peptide (D4R)
Catalog No : USB-D9018-35
417.25€
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| Product name | Dopamine Receptor, D4, Human, Control Peptide (D4R) | ||
|---|---|---|---|
| Catalog No | USB-D9018-35 | ||
| Supplier’s Catalog No | D9018-35 | ||
| Supplier | US Biologicals | ||
| Source antigen | Human synthetic peptide | ||
| Reactivity | Synthetic peptide consisting of 17aa sequence from human D4R within the N-terminus, extracellular domain. No significant sequence homology with other dopamine receptors (D1, D2, D3 or D5). Species Sequence Homology: monkey/chimps: 100%; mouse: 57% (387aa); rat: 57% (385aa) D4R receptors. | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | Highly purified | ||
| Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | Highly purified | ||
| Description | Control peptide for D9018-28 (antiserum) and D9018-30 (affinity purified antibody). Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. DR have been classified into either the D1-like (D1, D1B and D5) or D2-like (D2, D3 and D4). The two isoforms of D2R, D2 long (D2L) and short (D2S), are encoded by splice variants of a single gene and differ only by the presence of an additional 29aa in the intracellular domain 3 of the D2 long form. It may play a role in the coupling of the receptor to G-proteins. All members of this family have similar structure and contain 7 putative transmembrane domains. A given cell or tissue may express more than one DR. Specific radioligands do not exist that can differentiate between these DR. Therefore, specific antibodies are needed to distinguish, localize, and document changes in DR levels in cells and tissues under various normal and pathological conditions. Dopamine D4 Receptor is a 467aa, G-protein coupled and transmembrane receptor protein. Applications: Suitable for use in ELISA and Antibody Blocking, Not suitable for use in Western Blot due to low molecular weight. Other applications not tested. Recommended Dilution: Antibody Blocking: 5-10ug per 1ul D9018-28 (antiserum) or per 1ug D9018-30 (affinity purified antibody). ELISA: 1ug/ml. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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