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Categories: Peptides & Proteins / Proteins

Product name			Melanocortin Receptor 3, Human (MC3-R) (Control Peptide)
Catalog No			USB-M2868-25
Supplier’s Catalog No			M2868-25
Supplier			US Biologicals
Source antigen			Human synthetic peptide
Reactivity			An 18 aa peptide from the 1st extracellular domain of human MC3-R. Melanocortins are regulatory peptides formed by post-translational processing of pro-opiomelanocortin. Melanocortin peptides have been suggested to perform a variety of physiological roles ranging from control of behavior, memory, neurotrophic properties, antipyretic and modulation of immune system, etc. Their binding sites have been found distributed in tissues ranging from lachrymal and submandibular glands, pancreas, adipose tissue, bladder, duodenum, spleen, brain, gonadal tissues and malignant melanoma tumors. Five melanocortin receptors have been characterized to date. These include melanocyte-stimulating hormone receptor (MSH or MC1-R), corticoaderenal-specific ACTH receptor (MC2-R), melacortin-3 (MC3-R), melanocortin-4 (MC4-R) and melanocortin-5 receptor (MC5-R). MC3-R and MC4-R are distributed in brain whereas MC5-R has a broad distribution. human Melanocortin receptor (MC3-R) is a 360 amino acid transmembrane protein belonging to the family of G-Protein coupled receptors. It is a receptor for MSH (a,b,g) and ACTH. It is found in brain, placenta and gut tissues.
Cross reactivity
Applications
Molecular weight

Storage			-20°C
Other names
Grade			Highly Purified
Purity			Highly purified
Form			Supplied as 1mg/ml soln. in PBS, pH 7.4 and 0.02% sodium azide/Merthiolate
Reactivity life			12 months
Note			For reserch purpose only
Purity			Highly purified
Description			An 18 aa peptide from the 1st extracellular domain of human MC3-R. Melanocortins are regulatory peptides formed by post-translational processing of pro-opiomelanocortin. Melanocortin peptides have been suggested to perform a variety of physiological roles ranging from control of behavior, memory, neurotrophic properties, antipyretic and modulation of immune system, etc. Their binding sites have been found distributed in tissues ranging from lachrymal and submandibular glands, pancreas, adipose tissue, bladder, duodenum, spleen, brain, gonadal tissues and malignant melanoma tumors. Five melanocortin receptors have been characterized to date. These include melanocyte-stimulating hormone receptor (MSH or MC1-R), corticoaderenal-specific ACTH receptor (MC2-R), melacortin-3 (MC3-R), melanocortin-4 (MC4-R) and melanocortin-5 receptor (MC5-R). MC3-R and MC4-R are distributed in brain whereas MC5-R has a broad distribution. Human Melanocortin receptor (MC3-R) is a 360 amino acid transmembrane protein belonging to the family of G-Protein coupled receptors. It is a receptor for MSH (a,b,g) and ACTH. It is found in brain, placenta, and gut tissues.