KIR3DL1, aa361-444, Cytoplasmic Tail, Recombinant, Human, His-Tag (NKB1, nkat3, p70 KIR, Killer Cell Immunoglobulin (Ig)-like Receptor)
Catalog No : USB-K1862-30
564.38€
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| Product name | KIR3DL1, aa361-444, Cytoplasmic Tail, Recombinant, Human, His-Tag (NKB1, nkat3, p70 KIR, Killer Cell Immunoglobulin (Ig)-like Receptor) | ||
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| Catalog No | USB-K1862-30 | ||
| Supplier’s Catalog No | K1862-30 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 15 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥ 95% by SDS PAGE; Purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. | ||
| Form | Supplied as a liquid in 25mM Tris-HCl, pH 7.5 and 100mM sodium chloride. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥ 95% by SDS PAGE; Purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a redox buffer. | ||
| Description | The three Ig-domain from of inhibitory killer cell Ig-like receptor 1 (KIR3DL1, NKB1, nkat3, p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DLl recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR, which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. A His-tag fusion protein of KIR3DL1 cytoplasmic tail (aa361-444) was overexpressed as insoluble protein aggregates (inclusion bodies). Molecular Weight: 15kD (132 amino acids) Sequence: MRGSHHHHHH/ GMASMTGGQQ/ MGRDLYDDDD/ KDRWGSTSGT/ IDKLDIEFHL/ WCSNKKNAAV/ MDQEPAGNRT/ ANSEDSDEQD/ PEEVTYAQLD/ HCVFTQRKIT/ RPSQRPKTPP/ TDTILYTELP/ NAKPRSKVVS/ CP Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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