KIR3DL1, Recombinant, Human (NKB1, nkat3, p70 KIR, Killer Cell Immunoglobulin (Ig)-like Receptor)
Catalog No : USB-K1862-29H
377.02€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | KIR3DL1, Recombinant, Human (NKB1, nkat3, p70 KIR, Killer Cell Immunoglobulin (Ig)-like Receptor) | ||
|---|---|---|---|
| Catalog No | USB-K1862-29H | ||
| Supplier’s Catalog No | K1862-29H | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 15 | ||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ≥ 95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel. | ||
| Form | Supplied as a liquid in 25mM Tris-HCl, pH 7.5 and 100mM sodium chloride. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥ 95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel. | ||
| Description | The three Ig-domain from of inhibitory killer cell Ig-like receptor 1(KIR3DL1,NKB1, nkat3, p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DLl recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR, which contains two immunoreceptor tyrosine-based inhibition motifs(ITIMs), mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. Description: A His-tag fusion protein of KIR3DL1 cytoplasmic tail(361-444aa) was overexpressed as insoluble protein aggregates(inclusion bodies). Recombinant KIR3DL1 produced in E.Coli is a single,non-glycosylated polypeptide chain conjtaining 132 amino acids and having a molecular mass of 15kD. Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSTSGT IDKLDIEFHLWCSNKKNAAV MDQEPAGNRT ANSEDSDEQD PEEVTYAQLD HCVFTQRKIT RPSQRPKTPP TDTILYTELP NAKPRSKVVS CP Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles. | ||
Product Details
© 2020 Imugex All Rights Reserved