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Categories: Peptides & Proteins / Proteins

Product name			LAIR-1, Recombinant, Human (Leukocyte-associated Ig-like Receptor-1)
Catalog No			USB-L1100-02H
Supplier’s Catalog No			L1100-02H
Supplier			US Biologicals
Source antigen			Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight			11.5

Storage			-20°C
Other names
Grade			Highly Purified
Purity			≥ 95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Form			Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 50mM sodium chloride and 1mM EDTA.
Reactivity life			6 months
Note			For reserch purpose only
Purity			≥ 95% as determined by RP-HPLC, anion-exchange FPLC and/or reducing and non-reducing SDS-PAGE Silver Stained gel.
Description			LAIR-1 is a glycoprotein(~32kD) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells , B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. Description: The extracellular domain of LAIR-1(22-125aa) was overexpressed in E.coli, and purified by using conventional chromatography techniques. Recombinant LAIR-1 produced in E.Coli is a single,non-glycosylated polypeptide chain containing amino acids 105 and having a molecular mass of 11.5kD. Sequence: MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPSESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG Stability: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.