LYVE-1, Recombinant, Human (Lymphatic Vessel Endothelial Hyaluronic Acid Receptor, LYVE1, CRSBP1, Extracellular Link Domain Containing 1, Hyaluronic Acid Receptor, HAR, Lymphatic Endothelium Specific Hyaluronan Receptor, Lymphatic Vessel Endothelial Hyaluronan Receptor 1, XLKD1)
Catalog No : USB-L9375-05
496.57€
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| Product name | LYVE-1, Recombinant, Human (Lymphatic Vessel Endothelial Hyaluronic Acid Receptor, LYVE1, CRSBP1, Extracellular Link Domain Containing 1, Hyaluronic Acid Receptor, HAR, Lymphatic Endothelium Specific Hyaluronan Receptor, Lymphatic Vessel Endothelial Hyaluronan Receptor 1, XLKD1) | ||
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| Catalog No | USB-L9375-05 | ||
| Supplier’s Catalog No | L9375-05 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 36 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Purified | ||
| Purity | ≥90% SDS-PAGE and RP-HPLC. On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 36kD | ||
| Form | Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA and 20% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ≥90% SDS-PAGE and RP-HPLC. On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 36kD | ||
| Description | The pace of research into the lymphatic system continues to accelerate with the availability of new molecular markers. One such marker, LYVE-1, the lymphatic receptor for the extracellular matrix mucopolysaccharide hyaluronan, has been a key component of many important studies on embryonic and tumor-induced lymphangiogenesis, and continues to be used for the detection and isolation of lymphatic endothelial cells. However, LYVE-1 is interesting in its own right. Being a member of the Link protein family whose only other major hyaluronan receptor is directly involved in leukocyte migration and tumor metastasis, LYVE-1 is already implicated in the trafficking of cells within lymphatic vessels and lymph nodes. The current challenge is to determine the precise roles played by LYVE-1 and other scavenger type receptors in the immune functions of the lymphatics as well as to use LYVE-1 and other markers to investigate the way in which tumors exploit lymphatic vessels for metastasis. Applications: Suitable for use in ELISA, Inhibition Assays, and Western Blot. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, add a carrier protein (0.1% HSA or BSA), aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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