Glucagon-like Peptide 1 Receptor, Mouse, Control Peptide (GLP1R)
Catalog No : USB-G2040-38E
417.25€
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| Product name | Glucagon-like Peptide 1 Receptor, Mouse, Control Peptide (GLP1R) | ||
|---|---|---|---|
| Catalog No | USB-G2040-38E | ||
| Supplier’s Catalog No | G2040-38E | ||
| Supplier | US Biologicals | ||
| Source antigen | Mouse synthetic peptide | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | |||
| Storage | -20°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Purified | ||
| Purity | Purified | ||
| Form | Supplied as a liquid in PBS, pH 7.5. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | Purified | ||
| Description | Glucagon is a member of a multigene family comprising of Secretin, Vasoactive Intestinal Peptide (VIP), Gastric Inhibitory Peptide (GIP) and others like Glicentin and Oxyntomodulin (OXM), which differs from glucagon by C-terminal octapeptide. The glucagon precursor contains at least 3 intervening sequences that divide the protein-coding portion into 4 regions corresponding to the signal peptide and part of the N-terminal peptide, the remainder of the N-terminal peptide and glucagon, glucagon-like peptide-1 (GLP1), and GLP2. The GLP 1 & 2 stimulates intestinal growth and up regulates villus height in the small intestine, concomitant with increased crupt cell proliferation and decreased enterocyte apoptosis. The two GLP's are mainly produced in the A cells of the Islets of Langerhans in response to a drop in blood sugar concentration. GLP1 Receptor, a 489aa peptide in mouse, 463aa in rat and human (chr 6p21), it serves as receptor for GLP1. The activity of this receptor is mediated by G protein which activate adenylyl cyclase. GLP1 Receptor is mainly expressed in pancreatic islets, stomach, and lung. Source: 17aa peptide of mouse GLP1 Receptor, conjugated to KLH Localization: Mid-region Applications: Suitable for use in ELISA. Other applications not tested.. Recommended Dilutions: ELISA: 50-100ng/well. Optimal dilutions to be determined by he researcher. Species Sequence Homology: Human, Rat: 100% Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for 6 months at -20°C after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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