Natriuretic Peptide Receptor B, aa288-302, Human (NPR-B)

Catalog No : USB-N0019-65A
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Product name Natriuretic Peptide Receptor B, aa288-302, Human (NPR-B)
Catalog No USB-N0019-65A
Supplier’s Catalog No N0019-65A
Supplier US Biologicals
Source antigen Human
Reactivity Recognizes human NPR-B
Cross reactivity
Applications
Molecular weight
Storage -20°C
Other names
Grade Highly Purified
Purity ≥95% (HPLC)
Form Supplied as a lyophilized powder. No preservatives added. Reconstitute with 0.1% acetic acid.
Reactivity life 12 months
Note For reserch purpose only
Purity ≥95% (HPLC)
Description ANPB (natriuretic peptide receptor B) is one of two integral membrane receptors for natriuretic peptides. Both ANPA and ANPB contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain), an helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. ANPB is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with 0.1% acetic acid. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.