Imugex

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Categories: Peptides & Proteins / Proteins

Product name			mGluR5 (Metabotropic Glutamate Receptor)
Catalog No			USB-M3884-79M
Supplier’s Catalog No			M3884-79M
Supplier			US Biologicals
Source antigen
Reactivity
Cross reactivity			Mouse, Rat
Applications
Molecular weight

Storage			-20°C
Other names
Grade
Purity
Form			Supplied as a liquid.
Reactivity life			12 months
Note			For reserch purpose only
Purity
Description			Metabotropic glutamate receptors have been classified into three groups. In general, class I receptors (mGluR1 and mGluR5) mediate the excitation of neurons, whereas activation of class II (mGluR2 and mGluR3) and class III (mGluR4a, mGluR7a, mGluR7b and mGluR8) results in a depression of synaptic transmission. Class I mGluRs are localized in the postsynaptic membrane and are positively coupled to phospholipase C (PLC). Class II and class III mGluRs localize to the presynaptic membrane and are negatively coupled to adenylate cyclase. It has been speculated that mGluR2 and/or mGluR3 may play a role in the modulation of the mossy terminal function. Control Peptide for M3884-79D Applications: Suitable for use in Antibody Blocking. Other applications not tested. Recommended Dilution: Antibody Blocking: 1:100 – 1:1000 1 hour at room temperature. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.