RAP, Recombinant, Rat (Receptor Associated Protein)
Catalog No : USB-R1115-15A
760.94€
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| Product name | RAP, Recombinant, Rat (Receptor Associated Protein) | ||
|---|---|---|---|
| Catalog No | USB-R1115-15A | ||
| Supplier’s Catalog No | R1115-15A | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 40 | ||
| Storage | 4°C/-70°C | ||
|---|---|---|---|
| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (SDS-PAGE) | ||
| Form | Supplied as a lyophilized powder from TBS, pH 7.5, 0.1% BSA, 0.09% sodium azide. Reconstitute with 100ul ddH2O. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (SDS-PAGE) | ||
| Description | RAP binds with high affinity to certain members of the low-density lipoprotein (LDL) receptor family such as LDL receptor-related protein (LRP), gp330/megalin, and the very low-density lipoprotein (VLDL) receptor and, once bound to these receptors, antagonizes their ligand binding ability. Despite the presence of a putative signal sequence on RAP, this molecule is not secreted but remains cell-associated. RAP is contained primarily within the endoplasmic reticulum and Golgi compartments, with only a trace found at the cell surface and within the endosomal compartments. Genetic deletion of RAP in mice has no effect on LRP mRNA levels but does lead to incomplete processing of LRP in the brain and liver resulting in decreased LRP antigen levels in these organs. Rat his: RAP:c-myc fusion partner. Applications: Suitable for use as protein standard in 1D and 2D SDS gel electrophoresis, immunoblotting and receptor-binding studies. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4°C. Stable for 6 months after receipt at 4°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.r. | ||
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