Platelet Derived Growth Factor Receptor alpha Recombinant, Human, aa24-524, His-Tag (PDGFRa)

Catalog No : USB-P4258-03P
508.06€
0.00€

Shipping cost plus VAT not included , delivery in 7-14 business days

Product name Platelet Derived Growth Factor Receptor alpha Recombinant, Human, aa24-524, His-Tag (PDGFRa)
Catalog No USB-P4258-03P
Supplier’s Catalog No P4258-03P
Supplier US Biologicals
Source antigen Recombinant, E.coli
Reactivity
Cross reactivity
Applications
Molecular weight 58.4
Storage -20°C
Other names
Grade Purified
Purity ~85% (SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl buffer, pH8, 0.1M sodium chloride, 1mM DTT, 20% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity ~85% (SDS-PAGE)
Description PDGFRa, also known as platelet derived growth factor receptor alpha, is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. This protein can bind to both A and B subunits of PDGF. It is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. Purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Source: Recombinant corresponding to aa24-524 of human PDGFRa, fused to His-tag at N-terminal, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MQLSLPSILP NENEKVVQLN SSFSLRCFGE SEVSWQYPMS EEESSDVEIR NEENNSGLFV TVLEVSSASA AHTGLYTCYY NHTQTEENEL EGRHIYIYVP DPDVAFVPLG MTDYLVIVED DDSAIIPCRT TDPETPVTLH NSEGVVPASY DSRQGFNGTF TVGPYICEAT VKGKKFQTIP FNVYALKATS ELDLEMEALK TVYKSGETIV VTCAVFNNEV VDLQWTYPGE VKGKGITMLE EIKVPSIKLV YTLTVPEATV KDSGDYECAA RQATREVKEM KKVTISVHEK GFIEIKPTFS QLEAVNLHEV KHFVVEVRAY PPPRISWLKN NLTLIENLTE ITTDVEKIQE IRYRSKLKLI RAKEEDSGHY TIVAQNEDAV KSYTFELLTQ VPSSILDLVD DHHGSTGGQT VRCTAEGTPL PDIEWMICKD IKKCNNETSW TILANNVSNI ITEIHSRDRS TVEGRVTFAK VEETIAVRCL AKNLLGAENR ELKLVAPTLR SE Molecular Weight: ~58.4kDa (522aa) Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.