Imugex

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Categories: Peptides & Proteins / Proteins

Product name			ST2:Fc, Recombinant, Human (Interleukin-1 Receptor-like 1, IL-1 Receptor-like 1, IL1RL1, IL-33 Receptor, Interleukin-33 Receptor)
Catalog No			USB-045314
Supplier’s Catalog No			045314
Supplier			US Biologicals
Source antigen			Recombinant, Human, HEK 293 cells
Reactivity
Cross reactivity
Applications
Molecular weight			90

Storage			4°C/-20°C
Other names
Grade			Highly Purified
Purity			≥90% (SDS-PAGE)
Form			Supplied as a 0.2um-filtered solution in PBS, pH 7.2.
Reactivity life			6 months
Note			For reserch purpose only
Purity			≥90% (SDS-PAGE)
Description			The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L. Biological Activity: Interacts with human IL-33. Sequence: Signal peptide and the sequence of isoform 2 of human ST2 (aa 1-328) are fused at the C-terminus to the Fc portion of human IgG1. Storage and Stability: Short-term Storage: +4°C Long-term Storage: -20°C Working aliquots are stable for up to 3 months when stored at -20°C.