FLT4, Recombinant, Human, aa25-774, His-Tag (Vascular endothelial growth factor receptor 3, Fms-like tyrosine kinase 4, Tyrosine-protein kinase receptor FLT4)
Catalog No : USB-169973
471.28€
0.00€
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| Product name | FLT4, Recombinant, Human, aa25-774, His-Tag (Vascular endothelial growth factor receptor 3, Fms-like tyrosine kinase 4, Tyrosine-protein kinase receptor FLT4) | ||
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| Catalog No | USB-169973 | ||
| Supplier’s Catalog No | 169973 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, Insect cells | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 120 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~90% (SDS-PAGE, HPLC) | ||
| Form | Supplied as a lyophilized powder with no additives. Reconstitute with sterile dH2O to 0.1mg/ml. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~90% (SDS-PAGE, HPLC) | ||
| Description | The Flt-4 gene is widely expressed in the early embryo but becomes restricted to the lymphatic endothelial a latter stages of development. It is important for lymphangiogenesis. Both VEGF family members VEGF-C and VEGF-D have been shown to bind and activate VEGFR-3/FLT-4. Soluble FLT4 Human Recombinant fused with a carboxy-terminal 6X histidine-tag produced in baculovirus is a monomeric, glycosylated, polypeptide containing the extracellular part, 25-774 amino acids and having a total molecular mass of 120kD. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.The FLT4 is purified by proprietary chromatographic techniques. Source: Recombinant protein corresponding to aa25-774 from human FLT4, fused to 6X His-tag at C-terminus, expressed in insect cells. Molecular Weight: ~120kD Biological Activity: Measured by its ability to bind recombinant rat VEGF-C in a functional solid phase binding assay. Immobilised recombinant human VEGFR-3/FLT-4 at 5ug/ml can bind recombinant rat VEGF-C in a linear range of 8-500ng/ml. Endotoxin: <0.1ng/ug Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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