Estrogen Receptor Alpha, Recombinant, Human, aa1-300 (ERa)

Catalog No : USB-208886
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Product name Estrogen Receptor Alpha, Recombinant, Human, aa1-300 (ERa)
Catalog No USB-208886
Supplier’s Catalog No 208886
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 59
Storage -20°C
Other names
Grade Purified
Purity Purified (~90%)
Form Supplied as a liquid in 50mM Tris-acetate, pH 7.5, 1mM EDTA, 20% glycerol.
Reactivity life 12 months
Note For reserch purpose only
Purity Purified (~90%)
Description The ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains, labeled A through F. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. Source: Recombinant protein corresponding to human Estrogen Receptor alpha, encoding aa1-300, expressed in E. coli. Molecular Weight: ~59kD Applications: Suitable for use in ELISA, Western Blot and Inhibition Assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.