KIR2DS4, Recombinant, Human, aa1-202 (P58 KIR, CD158, CL-17, Natural Killer-Associated Transcript 8, NKAT-8, Killer Cell Immunoglobulin (Ig)-like Receptor)
Catalog No : USB-209052
417.25€
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| Product name | KIR2DS4, Recombinant, Human, aa1-202 (P58 KIR, CD158, CL-17, Natural Killer-Associated Transcript 8, NKAT-8, Killer Cell Immunoglobulin (Ig)-like Receptor) | ||
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| Catalog No | USB-209052 | ||
| Supplier’s Catalog No | 209052 | ||
| Supplier | US Biologicals | ||
| Source antigen | Recombinant, E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 22.2 | ||
| Storage | -20°C | ||
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| Other names | |||
| Grade | Highly Purified | ||
| Purity | ~95% (RP-HPLC, SDS-PAGE) | ||
| Form | Supplied as a liquid in 20mM Tris-HCl, pH 7.5. No preservative added. | ||
| Reactivity life | 12 months | ||
| Note | For reserch purpose only | ||
| Purity | ~95% (RP-HPLC, SDS-PAGE) | ||
| Description | Killer-cell immunoglobulin-like receptors (KIRs), are a family of cell surface glycoproteins found on Natural Killer (NK) Cells, which are important cells of the immune system. They control the killing function of these cells by interacting with MHC class I molecules, which are expressed on all cell types. This interaction allows them to identify virally infected cells or tumor cells that have a distinctive low level of Class I MHC on their surface. The majority of KIRs are inhibitory, which means that their recognition of MHC suppresses the cytotoxic activity of their NK cell. Only a limited number of KIRs have the capacity to activate cells. The KIR genes are found in a cluster on chromosome 19q13.4 within the 1Mb leukocyte receptor complex (LRC). KIR molecules are extremely polymorphic, meaning their gene sequences differ significantly between individuals, so that different individuals have different arrays/repertoires of KIR genes. Source: Recombinant protein corresponding to human KIR2DS4, a single, non-glycosylated polypeptide chain containing aa1-202, expressed in E. coli. Molecular Weight: ~22.2kD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | ||
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