LAIR-1, Recombinant, Human (Leukocyte-Associated Ig-Like Receptor 1)

Catalog No : USB-209063
417.25€
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Product name LAIR-1, Recombinant, Human (Leukocyte-Associated Ig-Like Receptor 1)
Catalog No USB-209063
Supplier’s Catalog No 209063
Supplier US Biologicals
Source antigen Recombinant, E. coli
Reactivity
Cross reactivity
Applications
Molecular weight 11.5
Storage -20°C
Other names
Grade Highly Purified
Purity ~95% (RP-HPLC, SDS-PAGE)
Form Supplied as a liquid in 20mM Tris-HCl, pH 7.5, 50mM sodium chloride, 1mM EDTA.
Reactivity life 12 months
Note For reserch purpose only
Purity ~95% (RP-HPLC, SDS-PAGE)
Description LAIR-1 is a glycoprotein (~32kD) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Inhibitory receptors control the immune response to prevent lysis of cells recognized as self. Lair1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. Source: Recombinant protein corresponding to human LAIR-1, a single, non-glycosylated polypeptide chain containing 105aa, expressed in E. coli. The extracellular domain of LAIR-1 (aa22-125) was overexpressed in E. coli. Molecular Weight: ~11.5kD Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.